We seek to determine whether we can reduce day 28 mortality in Zambian newborns by training traditional birth attendants a modified version of the neonatal resuscitation protocol (NRP) and by improving their abiltiy to identify sepsis and initiate antibiotics in the field.
This is a cluster randomized trial of the impact of providing additional training and supplies to traditional birth attendants in a rural setting in Zambia. 120 TBAs are randomized into intervention/control. Intervention TBAs receive NRP training, supplies for neonatal resuscitation, receiving blankets for thermoregulation, and amoxicillin tablets. Control TBAs continue according to prior standard of care. Primary outcome is mortality at 28 days life as a proportion of births attended by TBAs in each study arm.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
3,559
training in neonatal resuscitation and sepsis identification early treatment
continued with current standard of care for birth attendants
mortality
Time frame: day 28
perinatal mortality
Time frame: day zero
sepsis mortality
Time frame: deaths between days 1-28
cost effectiveness
Time frame: days 0-28
successful delivery of nevirapine prophylaxis to HIV exposed deliveries
Time frame: day zero umbilical cord dried blood spot
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