Organ protection, volatile anesthetics, postconditioning, hepatic surgery
This study aims at the evaluation of a potential attenuation of ischemic-reperfusion injury in the liver with sevoflurane postconditioning upon reperfusion.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
125
3.2 Vol % for postconditioning
University Hospital of Zurich
Zurich, Switzerland
Liver transaminase AST
Peak value
Time frame: Postoperative phase until discharge
ALT peak value
Time frame: Postoperative phase until discharge
Course of transaminases
Time frame: From the day before surgery, to 6 hours after surgery, up to postoperative day 7
Postoperative complications
Time frame: Postoperative phase until discharge
Length of hospital stay
Time frame: Postoperative phase until discharge
Need for prolonged intensive care unit stay (>24 hours)
Time frame: Postoperative phase until discharge
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