Influence of Nutrition on Nasal and Bronchial Affliction in Patients With Allergy on Grass-Pollen

N/ACompletedNCT00519740

Johann Wolfgang Goethe University Hospital120 enrolled

Overview

The study is meant to observe the influence of nutrition on nasal and bronchial discomfort in patients with allergy on grass pollen after specific bronchial provocation. Therefore, the investigators will record the patients' nutrition habits and measure the blood level of long chained polyunsaturated fatty-acids.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

120

Conditions

Bronchial Hyperreactivity Hypersensitivity Allergy Bronchial Asthma

Interventions

inhalative specific bronchial provocation with grass-pollenOTHER

Eligibility

Sex: ALLMin age: 12 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * age \>12 and \<45 years * informed consent * Known allergy on grass-pollen Exclusion Criteria: * age \<12 and \>45 years * Clinical asthma requiring regular inhalation * vital capacity \>80% * FEV1 \< 75% * Chronic disease * pregnancy * Inhalative or systemic steroid use * substance abuse * incapability of understanding the study's purpose and performance

Locations (1)

Goethe University, Department of Pulmonology

Frankfurt am Main, Hesse, Germany

Outcomes

Primary Outcomes

correlation of the blood fatty-acid level and bronchial hyperreactivity, measured as the exhaled NO.

Time frame: aug 2006 - feb 2007

Data from ClinicalTrials.gov

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