Radiolabel Study In Healthy Volunteers For Insomnia-Targeting Drug

Inclusion criteria: * Healthy males, aged 30-55 years inclusive. * Body weight more or equal to 50kg with a BMI (body mass index) between 18.5-29.9kg/m2 inclusive. * Healthy as based on a medical evaluation consisting of medical history, physical examination, lab tests on blood and urine and cardiovascular monitoring. LH, FSH and testosterone hormones must be within normal reference range. Exclusion criteria: * Positive urine drug screen or alcohol breath test at screening visit. * Average weekly alcohol intake of more than 21 units or average daily intake of more than 3 units. * Grapefruit or grapefruit juice intake 7 days before dosing and until the last blood sample is taken. * Any subject who is not prepared to eat standard meals in the clinic or is a vegetarian. * Participated in a clinical trial for a new drug within 30 days or 5 half-lives or twice the duration of that drugs effect before the dosing day for this study. * Exposure to 4 new drugs in clinical trials within the last 12 months before dosing in this study. * Use of any medications (prescribed or non-prescribed including vitamins and herbal supplements) within 7 days before dosing in this study. * Participation in this study would result in the subject donating more than 500ml in a 56 day period. * Regular use of tobacco or nicotine-containing products within 6 months of screening. * Unwillingness to abstain from sexual intercourse with pregnant or lactating women from dosing until 84 days after. * Unwillingness to use contraception and have female partner use contraception if she could become pregnant for 84 days after dosing. * Unwillingness to abstain from strenuous physical activity for 48 hours before screening and in the 72 hours before and 48 hours after the treatment period. * Administration of radiolabelled substances or exposure to significant radiation (eg serial X-rays or CT scans, barium meal etc)within the past 12 months from screening.