Integrase Inhibitor (MK-0518) Viral Decay

Inclusion Criteria: 1. Participant must be HIV-1 infected 2. Participant must be 18 years old 3. Participant must be taking first standard cART with 2-3 NRTIs and 1-2 PIs or an NNRTI for at least four years (first cART regimen may include changes due to toxicity but not due to virologic failure). 4. Participant must have a VL \< 50 copies/ml (using the standard available methods of detection) during the entire time on standard cART except for initial fall of VL and a maximum of two non-consecutive blips of \< 100 copies/ml that the study investigator deems to be not clinically significant 5. Female participant must agree to use two methods of birth control or abstinence during the period of the study 6. Participant has to have signed full informed consent Exclusion Criteria: 1. Participant who would have difficulty participating in a trial due to non-adherence or substance abuse 2. Participant who has taken mono or dual antiretroviral therapy in the past 3. Participant who has had a VL \> 50 copies/ml on any antiretroviral regimen 4. Participant with any of the following abnormal laboratory test results in screening: * Hemoglobin \< 100 g/L * Neutrophil count \< 750 cells/L * Platelet count \< 50,000 cells/L * AST or ALT \> 5X the upper limit of normal * Creatinine \> 250 mol/L 5. Participant with a malignancy 6. Participant with other significant underlying disease (non-HIV) that might impinge upon disease progression or death 7. Participant with an active AIDS-defining illness in the past six months 8. Participant who is pregnant