Cryosurvival of Embryos From Dysmorphic Oocytes

V.K.V. American Hospital, Istanbul

Overview

Various morphological abnormalities of human oocytes were reported to detrimentally affect embryo development. We observed development of frozen thawed embryos derived from oocytes with normal or abnormal morphological features to the blastocyst stage. Cytoplasmic abnormalities of the oocytes were found to negatively affect cryosurvival potential of the embryos.

Study Type

OBSERVATIONAL

Conditions

Cryopreservation Blastocyst

Interventions

Cryopreservation, thawing and blastocyst culturePROCEDURE

Good quality human embryos were frozen - thawed and cultured to the blastocyst stage.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Human embryos derived from morphologically normal or abnormal mature oocytes that fertilized normally by microinjection procedure. * Embryos were obtained from couples who refused to freeze their supernumerary embryos after fresh embryo transfer in an assisted reproduction treatment cycle. Exclusion Criteria: * Embryos obtained after microinjection to immature oocytes taht were in vitro matured in culture. * Embryos obtained from abnormally fertilized zygotes.

Locations (1)

VKV American Hospital

Istanbul, Turkey (Türkiye)

Data from ClinicalTrials.gov

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