Metabolic Changes in Hypothyroid Patients

University of Aarhus22 enrolled

Overview

Hypothyroidism is a frequent condition in danish women, but often overlooked. Along with fatigue one of the main symptoms is weight gain as a result to significantly decreased energy expenditure. This study was undertaken to elucidate changes in glucose, lipid and amino acid turnover in these patients.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Hypothyroidism

Interventions

L-thyroxineDRUG

The hypothyroid patients receive usual treatment with L-thyroxine in our out patient clinic. The doctors there subscribe the medication, this study has no protocol regarding this, we observe the patients again after having been biochemically euthyroid for at least two months.

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Newly diagnosed hypothyroidism with tsh over 40 mU/L, etiology chronic autoimmune thyroiditis * Healthy controls matched regarding sex, age and body mass index Exclusion Criteria: * Pregnancy, breastfeeding

Locations (1)

Aarhus University Hospital

Aarhus, Denmark

Data from ClinicalTrials.gov

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