A Phase II Study of a Continuous Hepatic Arterial Infusion Combination Therapy With OPC-18 and 5-FU in Patients With Highly Advanced Hepatocellular Carcinoma

Inclusion Criteria: * Patients who are histologically or clinically (diagnostic imaging and tumor marker) diagnosed with hepatocellular carcinoma * Patients with a measurable lesion by contrast CT * Patients with no remote metastasis (extrahepatic metastasis), confirmed by X-ray, CT, MRI, or other means if necessary * Patients who have not previously received intra-arterial hepatic chemotherapy Exclusion Criteria: * Patients receiving the herbal medicine shosaikoto * Patients with autoimmune hepatitis * Patients with a history of hypersensitivity to OPC-18 or other interferon preparations