A Clinical Study of Curcuminoids in the Treatment of Oral Lichen Planus

Inclusion Criteria: * Patients presenting to the UCSF oral medicine clinic diagnosed with either the atrophic or the erosive form of oral lichen planus * Study subjects must have a symptom score between 3 to 8 at the time of entry into the study. (Range of scale: zero to ten with zero being no symptoms and ten being the worst imaginable symptoms. * Study subjects will have discontinued systemic and/or topical steroids and/or curcuminoids for at least 2 weeks before entry into the study. Exclusion Criteria: * Pregnancy, lactation or unwillingness to use an effective method of contraception. An attempt will be made to ascertain the date of the last menstrual period among eligible pre-menopausal women. If pregnancy cannot be ruled out, a pregnancy test will be provided to the women before enrollment into the study. - Patients younger than 21 years of age. * Patients who cannot return for a follow-up visit at two weeks after enrollment. * Patients who have a medical contraindication to discontinuation of systemic steroids eg. those on long term corticosteroid therapy. - Patients with a history of gastro-esophageal reflux disease, gastric / duodenal ulcers, or gallstones. * Patients with elevated liver enzymes; * Patients on anticoagulants or antiplatelet medications. * Patients undergoing orthodontic treatment. * Patients who don't read, speak or understand English.