Switching From Morphine to Oral Methadone Plus Acetaminophen in the Treatment of Cancer Pain

Overview

The purpose of this study is to determine whether oral methadone plus acetaminophen can substitute morphine in the treatment of cancer pain.

Opioids are the mainstay of moderate-to-severe cancer pain management. Although morphine is the most commonly used, methadone has some advantages such as higher potency, lower cost and longer administration intervals. To minimize the time necessary to achieve the equianalgesic effect after a switching from morphine to methadone, acetaminophen was added in the treatment.

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Central Contacts