A Single Dose Comfort Comparison of Travatan Z in One Eye Versus Xalatan in the Opposite Eye in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension

Alcon Research54 enrolled

Overview

The purpose of this study is to compare the comfort of Travatan Z in one eye and Xalatan in the opposite eye in patients with primary open-angle glaucoma or ocular hypertension.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Open-Angle Glaucoma Ocular Hypertension

Interventions

Travoprost ophthalmic solution 0.004% with SofZia® preservative system (TRAVATAN Z®)DRUG

Ophthalmic solution for the treatment of open-angle glaucoma or ocular hypertension, one drop, single dose. Referred to as travoprost.

Latanoprost ophthalmic solution 0.005% (XALATAN®)DRUG

Ophthalmic solution for the treatment of open-angle glaucoma or ocular hypertension, one drop, single dose. Referred to as latanoprost.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 18 years of age or older. * Clinical diagnosis of ocular hypertension, primary open-angle, pigment dispersion, or exfoliation glaucoma in both eyes. * Best corrected visual acuity of 20/200 Snellen or better in each eye. * Intraocular pressure within protocol-specified range. * Other protocol-defined inclusion criteria may apply. Exclusion Criteria: * Any abnormality preventing reliable applanation tonometry in the study eye(s). * Any eye conditions or procedures as specified in protocol. * Progressive retinal or optic nerve disease from any cause. * Use of contact lenses in the study eye(s). * Other protocol-defined exclusion criteria may apply.

Outcomes

Primary Outcomes

Comfort Immediately After Dosing

Comfort was assessed by the patient and recorded on a scale of 0 to 100, with 0 = perfect comfort and 100 = worse discomfort imaginable.

Time frame: 5 seconds

Data from ClinicalTrials.gov

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