Prospective, randomized, open-label study to assess the efficacy and safety of hypertonic lactate solution, compared to Ringer's Lactate as fluid resuscitation to maintain hemodynamic stability in post-coronary artery bypass grafting(CABG) patients. Patients who were eligible received either hypertonic lactate solution or Ringer's Lactate post-CABG in the ICU when fluid resuscitation was needed.
Prospective, randomized, open-label study to assess the efficacy and safety of hypertonic lactate solution, compared to Ringer's Lactate as fluid resuscitation to maintain hemodynamic stability in post-coronary artery bypass grafting(CABG) patients. Patients who were eligible received either hypertonic lactate solution or Ringer's Lactate post-CABG observed in the first 12 hours in the ICU when fluid resuscitation was needed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
230
Parenteral solution administered to a maximal volume of 10 ml/kg BW over the first 12 hours post-CABG
Parenteral solution administered to a maximal dose of 30 ml/kg BW over the first 12 hours post-CABG
National Cardiac Center, Department of Surgery and Intensive Care Unit, Harapan Kita Hospital
Jakarta, Jakarta Special Capital Region, Indonesia
hemodynamic stability
Time frame: 12 hours post-CABG surgery
Safety of hypertonic sodium lactate for maintaining the hemodynamic stability
Time frame: 12 hours post-CABG surgery
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