Prophylaxis of Ventilator Associated Pneumonia by Continuous Lateral Rotation Therapy

Medical University of Vienna150 enrolled

Overview

Hypothesis: Ventilator associated pneumonia (VAP) in critically ill patients may be prevented by continuous lateral rotation therapy (CLRT) using specially designed, motor driven beds. Patients are randomized to CLRT or supine position if mechanically ventilated and not suffering from pneumonia or ARDS within 48 hours after intubation. Prophylaxis of VAP is standardized in both groups. Primary endpoint is incidence of VAP, secondary endpoints are length of ventilation, length of stay and mortality.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

150

Conditions

Pneumonia, Ventilator-Associated

Interventions

Continuous lateral rotation therapyPROCEDURE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 89 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Mechanically ventilated * Intubated not longer than 48 h * Medical cause for ICU admission * Expected to be ventilated for \> 48 hours Exclusion Criteria: * Pneumonia or ARDS present * Postoperative patient

Locations (1)

Vienna General Hospital, Medical University of Vienna

Vienna, Austria

Outcomes

Primary Outcomes

Ventilator associated pneumonia

Secondary Outcomes

Length of hospital stay

Length of mechanical ventilation

ICU and hospital Mortality

Data from ClinicalTrials.gov

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