Study of the Efficacy of Preoperative Cefuroxime Prophylaxis to Prevent Surgical Site Infection in Herniated Disk Surgery

Inclusion Criteria: * Age older than 18 * spinal surgery for herniated disk Exclusion Criteria: * known or suspected hypersensitivity to cephalosporins * type I hypersensitivity to betalactamic antibiotics * severe renal function impairment * acquired immune deficiency syndrome (AIDS) or other conditions of severe immuno-suppression * antibiotic therapy for concomitant infection at the time of surgery * pregnancy * refusal to participate