Effects of Coenzyme Q10 in PSP and CBD

Inclusion Criteria: * Patients fulfilling the diagnostic criteria of PSP and CBD (above) and who were diagnosed within the past 5 years * Age \> 40 * Subjects receiving anticholinergics, amantadine, dopamine agonists, carbidopa/levodopa, eldepryl, or comtan must be on a stable dose for at least 30 days prior to baseline visit. * Patients agreeable to participate in the study. Exclusion Criteria: * Prior or concurrent therapy with anticholinergics, amantadine,a dopamine agonist,carbidopa/levodopa or comtan within 30 days of the baseline visit. * Parkinsons disease or any other atypical parkinsonism; Parkinsonism due to drugs. * History of pallidotomy, thalamotomy, deep brain stimulation or fetal tissue transplant. * Previous use of coenzyme Q10 within 60 days of the baseline visit.