Does Quality of Life Improve in Multiple Sclerosis Patients Treated With Interferon Beta-1a?

Inclusion Criteria: * Relapsing Remitting Multiple Sclerosis * Interferon naïve * Eligible for interferon beta-1a (AVONEX®) therapy as per Summary of Product Characteristics: * Subject has had relapsing MS for \> 1 year * Subject has had experienced 2 exacerbations in the last 2 years * Subject had an EDSS \[5\] score of \< 5.5 * Subject was ambulant Exclusion Criteria: * Diagnosis of MS defined as progressive * History of any significant cardiac, hepatic, pulmonary, or renal disease; immune deficiency; or other medical conditions that would preclude therapy with interferon beta * History of severe allergic or anaphylactic reactions or history of hypersensitivity to human albumin * History of seizures within the 3 months prior to starting this study * History of intolerance to acetaminophen (paracetamol), ibuprofen, naproxen or other NSAIDs, that would preclude use of at least one of these during the study * History of intolerance to interferons * Previous use of interferon beta * Female subjects who were pregnant or breast-feeding * For female subjects, unless postmenopausal or surgically sterile, unwillingness to practice effective contraception