To determine whether iron deficiency anemia can be an indication for the treatment of subclinical hypothyroidism.
51 Patients presented to our university outpatient internal medicine clinic who are found to have iron deficiency anemia coexisting with subclinical hypothyroidism have been included in this study. Patients were randomly assigned to oral iron or oral iron plus levothyroxin therapy. The physician and the patients did not know who received oral iron only or oral iron plus levothyroxine treatment. Hematologic parameters as well as serum iron, ferritin and iron binding capacity were being measured at the beginning and 3 months after treatment in both groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Combination of ferrous sulfate tablet 325mg plus levothyroxine tablet 25 micrograms, po, TID
Duzce University School of Medicine
Düzce, Turkey (Türkiye)
Significant improvement in Hgb and RBC
Time frame: 3 months
Significant improvement in serum iron, ferritin, TIBC and possibly in serum TSH and free T4 levels.
Time frame: 3 months
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