Immunotherapy With Depigmented and Polymerized Allergen Extract of Olea Europaea (GPIT)

Inclusion Criteria: * Positive suggestive clinical history of allergic seasonal rhinitis or rhinoconjunctivitis * Patients of both gender \> 18 years old * Positive prick test results using non modified Olea europaea allergen extract (wheal size \> 3mm2) * Specific IgE to Olea europaea * Written informed consent Exclusion Criteria: * Use of immunotherapy during the last four years. * Any contraindication for the use of immunotherapy in accordance with European Allergy and Clinical Immunology Immunotherapy Subcommittee criteria: * Treatment with ß-blockers * Coexistence of immunopathological diseases (e.g. of the liver, kidney, the nervous system, thyroid gland, rheumatic diseases) in which autoimmune mechanisms play a role * Patients suffering from immune deficiencies * Patients with serious psychiatric / psychological disturbances * In addition, the following was considered as exclusion criteria: * Pregnant or/ in lactation patients * Patients aspirin intolerance