This study plans to investigate whether a reduced dose of bupivacaine (a local anesthetic numbing drug) injected into the spinal space for a total knee replacement will result in a shorter time to discharge from the recovery room while maintaining adequate surgical anesthesia.
With the doses of bupivacaine currently being used in spinal anesthetics at our institution, patients' sensory blocks are often much higher than needed to achieve adequate surgical anesthesia. This translates into a prolonged waiting period in the recovery room before the level regresses down to the pre-existing standard for discharge to the ward, as well as the pre-existing level before a post-operative nerve block for extended pain relief can be performed. This prolonged period in the recovery room leads to general delays in operating room usage and thus surgical cancellations. The excessive drug doses currently used also put patients at risk for increasing side effects including low blood pressure, slow heart rates, and nausea and vomiting. By using a reduced dose of bupivacaine in a spinal anesthetic for a one sided knee replacement, we hope to significantly reduce the recovery room waiting times until the criteria for recovery room discharge or completion of a post-operative nerve block are met, while still providing adequate surgical anesthesia. Patients will receive either 9 mg (intervention dose) or 13 mg (control dose) of bupivacaine through a spinal injection. Once the patients enter the recovery room after surgery the level of their sensory block will be tested as per usual protocol by the recovery room nurses every 15 minutes until a predefined level has been reached, and the two groups will be compared.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
140
Bupivacaine 9 mg intrathecal single shot injection at start of surgery
Bupivacaine 13 mg intrathecal single shot injection at start of surgery
Kingston General Hospital
Kingston, Ontario, Canada
Time from spinal injection of bupivicaine until recovery room discharge criteria met.
Time frame: Until recovery room discharge post surgery
Need for pharmacologic rescue from inadequate spinal block during the procedure.
Time frame: Until end of surgery
Time from entrance into recovery room until criteria for a recovery room discharge are met
Time frame: Until recovery room discharge criteria are met
Time from entrance into recovery room until criteria for a femoral nerve block for post-operative pain control are met
Time frame: Until criteria are met for post operative nerve block in recovery room
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