Adult ALL Treatment at Diagnosis

Gruppo Italiano Malattie EMatologiche dell'Adulto

Overview

The present study has been designed to give participating centers the possibility of better understanding the diagnostic and prognostic factors of ALL patients.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Conditions

Leukemia, Lymphocytic, Acute

Interventions

VincristineDRUG

Steroids pre-treatment

Vincristin, Daunorubicine, Asparaginase, MethotrexateDRUG

Induction therapy

Eligibility

Sex: ALLMin age: 14 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis of acute lymphoblastic leukemia (ALL) * Negative myeloperoxidase stain * Phenotype T (ALL-T) and B(ALL-B) Exclusion Criteria: * Creatinine \> 2.5mg/dL after adequate hydratation * LVEF \<50% * Presence of documented infections not responding to antibiotic and/or antifungal therapy * Presence of concomitant malignant diseases * Absence of any psychological condition that does not allow to intake high doses of cortisone * Patients who have received any antineoplastic chemiotherapy for more than 5 days * Patients who have received any steroids for more than 10 days

Locations (5)

Az. Ospedaliera S. G. Moscati

Avellino, Italy

Ist.Ematologia e Oncologia Medica L.e A. Seragnoli

Bologna, Italy

Ospedale Reg. A di Summa

Brindisi, Italy

Istituto di Ematologia- Ospedale San Carlo

Potenza, Italy

Data from ClinicalTrials.gov

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