Opioid-potentiated Volative Anaesthetic Vs. Remifentanil And Propofol During Abdominal Aortic Aneurysm Surgery

Sykehuset i Vestfold HF193 enrolled

Overview

Comparing 2 different anaesthetic methods during abdominal aortic aneurysm surgery. The patients will be followed up 30 days postoperative. Number of patients included will be 200. Perioperative details will be analyzed.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

193

Conditions

Aortic Diseases Abdominal Aneurysm Surgery

Interventions

PropofolDRUG

Infusion intravenously (IV) 0-10 mg/kg/h

SevofluraneDRUG

0,7-1,5 MAC

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who are planned for open, elective abdominal aortic aneurysm surgery. * ASA group 1-4. Exclusion Criteria: * Patients below 18 years. * Patients who are included in other pharmaceutical studies. * Opioids-, benzodiazepins-, antiepileptic drugs-, alcohol- and α2-agonists abuse. * Pregnant and breastfeeding women. * Patients with familiar history of malignant hyperthermia. * Patients with known hypersensitivity for opioids, propofol or volative anaesthetics. * Patients with considerable arrythmia (atrial fibrillation /atrial flutter is acceptable). Uncontrolled hypertension, serious psychiatric disease. * Patients with unstable angina pectoris or myocardial infarction last month before inclusion. * Acute abdominal aortic surgery. Acute dissection or rupture. * Planned laparoscopic abdominal aortic aneurysm surgery.

Locations (1)

Sykehuset i Vestfold HF

Tønsberg, Norway

Data from ClinicalTrials.gov

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