Measurement Skin Temperature During Pulsed Laser Exposure

University of California, Irvine118 enrolled

Overview

Lasers are the treatment modality of choice for Port Wine Stain birthmarks.The epidermis is not totally spared due to partial absorption of energy therein by melanin that presents an optical barrier through which the light must pass to reach the underlying blood vessels. Absorption of laser energy by melanin causes localized heating in the epidermis, which may, if not controlled, produce permanent complications such as hypertrophic scarring or dyspigmentation.

The researchers want to establish a correlation between non-invasive skin temperature measurements and the minimum laser energy during skin laser treatment using cryogen spray cooling. This study would eliminate the need for test pulses to estimate the safe and acceptable radiant exposure prior to laser treatment.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

118

Conditions

Port-Wine Stain

Interventions

cooling spray during laser treatmentPROCEDURE

skin temperature measurement

Eligibility

Sex: ALLMin age: 7 YearsMax age: 75 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 7 years of age and older with diagnosis of port wine stain birthmark * 18 years of age and older with no port wine stain * non-pregnant women * apparent good health Exclusion Criteria: * age less than 7 years old * pregnant women * history of photodermatoses or skin cancer * current use of photosensitizing drugs

Locations (1)

Beckman Laser Institute Medical Clinic University of California Irvine

Irvine, California, United States

Outcomes

Primary Outcomes

skin temperature during laser treatment

Time frame: 90 days

Data from ClinicalTrials.gov

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