Weekly Vaccination With Copaxone as a Potential Therapy for Dry Age-related Macular Degeneration

The New York Eye & Ear Infirmary15 enrolled

Overview

The purpose of the project is to investigate in eyes with dry AMD, the efficacy and safety as preventive therapy of the immunomodulatory substance named copaxone which had been proven as safe and effective agent for a neurodegenerative disease, in arresting the progression as well as the conversion of dry AMD to wet AMD. The hypothesis that the immunomodulatory agent copaxone proven for a neurodegenerative disease may work in the eye is revolutionary and may open a new avenue of preventive treatment for the disease which is the major cause of legal blindness in the industrial world

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Dry Age Related Macular Degeneration

Interventions

Eligibility

Sex: ALLMin age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Dry AMD in one or both eyes 2. Age 50 or above of either gender 3. Signed informed consent. Exclusion Criteria: 1. Known sensitivity to Mannitol or Copaxone. 2. Skin disease or active infection of skin. 3. Active fever or active treatment for infection. 4. History of other uncontrolled systemic active disease. 5. Premenopausal females not using reliable birth control. 6. Sensitivity to fluorescein or iodine. 7. Inability to comply with study procedures.

Weekly Vaccination With Copaxone as a Potential Therapy for Dry Age-related Macular Degeneration

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes