Biochemical Marker to Predict the Recurrence of Atrial Fibrillation After Surgical Maze Procedure

Samsung Medical Center86 enrolled

Overview

The role of plasma NT-proBNP, hsCRP, TIMP-1(Tissue inhibitors of MetalloProteinase-1),TGF-b, MMP-3(Matrix MetalloProteinase-3), and pro-MMP-1 in predicting the recurrence of AF after surgical Maze procedure. The association of expression of CTGF, TGF-b, BNP, ANP, collagen-1, and collagen-3 in LA with the recurrence of AF after surgical Maze procedure.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Atrial Fibrillation

Eligibility

Sex: ALLMin age: 30 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * The patients who have valvular heart disease with atrial fibrillation and are scheduled for operation Exclusion Criteria: * Coronary heart disease * Congestive heart failure

Locations (1)

Samsung Medical Center

Seoul, South Korea

Outcomes

Primary Outcomes

AF recurrence

Time frame: year

Data from ClinicalTrials.gov

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