Simvastatin Reduces Adiponectin Levels and Insulin Sensitivity

Gachon University Gil Medical Center

Overview

We hypothesized simvastatin may reduce adiponectin levels and insulin sensitivity in overweight hypercholesterolemic patients.

Study Type

OBSERVATIONAL

Conditions

Hypercholesterolemia

Eligibility

Sex: ALLMin age: 25 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Low-density lipoprotein cholesterol levels more than 100 and body mass index more than 23.0 Exclusion Criteria: * Patients with overt liver disease * Chronic renal failure * Hypothyroidism, myopathy * Uncontrolled diabetes * Severe hypertension, stroke * Acute coronary events * Coronary revascularization within the preceding 3 months, or * Alcohol abuse.

Locations (1)

Gil Medical Center, Gachon University

Incheon, South Korea

Outcomes

Primary Outcomes

simvastatin may reduce adiponectin levels and insulin sensitivity in overweight hypercholesterolemic patients

Data from ClinicalTrials.gov

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