Relationship Between Microcirculatory Flow Alterations and Tissue Metabolism

Frisius Medisch Centrum30 enrolled

Overview

The purpose of this study is to correlate microcirculatory flow and rectal anaerobe cellular CO2 production in patients after cardiac surgery. The hypothesis is that such a correlation exists.

Sidestream Darkfield imaging is used to determine rectal microcirculatory flow in patients after postoperative cardiac surgery. At the same time PCO2 gap is established by monitoring rectal CO2 (tonometry) and arterial CO2 After initial enrollment and first analysis we also includes a control group with equal inclusion criteria for sublingual SDF imaging.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Cardiac Surgery

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * cardiac surgery * informed consent * age \> 18 Exclusion Criteria: * pregnancy * off pump procedure * rectal fecal contamination

Locations (1)

Department of ICU

Leeuwarden, PO Box 888, Netherlands

Outcomes

Primary Outcomes

Relation between MFI (by SDF) and capno

Time frame: 6 months

Secondary Outcomes

Relevance of changes in flow and metabolism

Time frame: 6 months

Data from ClinicalTrials.gov

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