The Active After Cancer Trial (AACT)

N/AActive Not RecruitingNCT00548236

Dana-Farber Cancer Institute120 enrolled

Overview

This study is being done to determine whether a telephone-based counseling intervention can help survivors of breast and colorectal cancer increase their weekly physical activity. Observational evidence suggests that physical activity after breast and colorectal cancer diagnosis decreases recurrence rates. Unfortunately, many people become less active during cancer therapy, and a substantial proportion never return to pre-diagnosis levels of physical activity. This study looks to see if people who have recently finished chemotherapy for breast, colon or rectal cancer can be motivated to increase their exercise by talking to an exercise specialist over the phone. The study also looks at changes in mood, fatigue, fitness, fat distribution and weight.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

120

Conditions

Breast Cancer Colorectal Cancer

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Histologically confirmed stage I-III breast or colorectal cancer * 18 years of age or older * Completed adjuvant treatment(for current malignancy) * Completion of all adjuvant chemotherapy and radiation (with the exception of adjuvant herceptin and/or tamoxifen/aromatase inhibitor therapy for breast cancer patients) between 2 and 36 months prior to enrollment * Ability to speak and read English * Willingness to be randomized * Medical clearance from an oncologist or primary care physician stating the participant is able to participate in an unsupervised, moderate-intensity physical activity program * No major surgery within 2 months of study enrollment or planned during study period Exclusion Criteria: * Metastatic cancer * Uncontrolled intercurrent illness including, but not limited to, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness that would limit compliance with study requirements * Plans to have hip or knee replacement within a year * Participation in more than 60 minutes a week of moderate-intensity recreational activity as assessed by the International Physical Activity Questionnaire Short Form * BMI \>47

Locations (9)

University of California at San Diego

La Jolla, California, United States

University of California San Francisco

San Francisco, California, United States

Dana-Farber Cancer Institute

Boston, Massachusetts, United States

New Hampshire Oncology Hematology

Concord, New Hampshire, United States

Lakes Regional Healthcare Hematology Oncology

Hooksett, New Hampshire, United States

Rosewell Park Cancer Institute

Buffalo, New York, United States

Hematology Oncology Associates of Central New York

East Syracuse, New York, United States

Ohio State University

Columbus, Ohio, United States

Vermont Cancer Center

Burlington, Vermont, United States

Outcomes

Primary Outcomes

To evaluate the ability of a multi-center, telephone-based physical activity intervention to increase weekly physical activity levels in sedentary patients treated with adjuvant chemotherapy for Stage I-III breast or colorectal cancer.

Time frame: months

Secondary Outcomes

To evaluate the impact of a physical activity intervention upon fitness, exercise self-efficacy, anthropometric measures, and quality of life in a group of patients with stage I-III breast or colorectal cancer.

Time frame: months