Study of Bathing With Chlorhexidine Impregnated Cloths on Nosocomial Infections in the Pediatric Intensive Care Unit

Johns Hopkins University5,659 enrolled

Overview

The investigators propose to conduct a large clinical study to determine if daily bathing with chlorhexidine impregnated cloths will reduce the incidence of healthcare-associated infections in the Pediatric Intensive Care Unit (PICU).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

5,659

Conditions

Nosocomial Infections

Interventions

2% Chlorhexidine gluconate clothDRUG

Daily bathing

Eligibility

Sex: ALLMin age: 2 MonthsMax age: 25 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients in pediatric intensive care unit Exclusion Criteria: * Patients with a history of an allergic reaction to chlorhexidine * Patients less than 2 months of age * Patients with severe skin disease or burn * Patients with an indwelling epidural catheter or lumbar drain

Locations (5)

Children's National Medical Center

Washington D.C., District of Columbia, United States

Johns Hopkins Hospital

Baltimore, Maryland, United States

Saint Louis Children's Hospital

St Louis, Missouri, United States

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States

Outcomes

Primary Outcomes

Bacteremia

incidence of bacteremia comparing those in treatment and control groups

Time frame: participants were followed for the duration of ICU stay, median stay 3 days

Secondary Outcomes

Central Line Associated-bloodstream Infection (CLABSI)

Comparing incidence of central line-associated bloodstream infections between treatment and control groups

Time frame: participants were followed for the duration of ICU stay, median stay 3 days

Data from ClinicalTrials.gov

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