The purpose of this study is to compare omega-3 fatty acids with placebo for efficacy in retardation of increase of serum creatinine(SCr) in IgA Nephropathy
In the current clinical study, attempts are made to assess the safety and efficacy of omega-3 fatty acids by comparing between omega-3 fatty acids and the placebo in Korean patients with IgA nephropathy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
152
Dosage form :1g soft capsule Dosage : two capsules, twice a day.
Seoul National University Bundang Hospital
Seongnam, Kyeonggi-do, South Korea
Seoul National University Hospital
Seoul, South Korea
Kyhung Hee University medical center
Seoul, South Korea
Samsumg Medical Center
Seoul, South Korea
The rate of number of patients that 50% or more increase in SCr after 42 months
Time frame: 42 months
The rate of number of patients that 50% or more increase in SCr after 6, 12, 24 and 36 months
Time frame: 42 months
Mean change of SCr, estimated GFR, urine Protein/Creatinine ratio, urine Albumin/Creatinine ratio, serum Cystatin C, Lipid profile
Time frame: 42 months
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Kangnam St. May's Hospital
Seoul, South Korea