A Study Investigating the Concentrations of Darapladib in Blood and the Safety of This Compound in Healthy Japanese Men

Inclusion criteria: * Japanese males, 20-64 years of age, inclusive * Body weight \>50Kg * Body Mass Index (BMI): 18-28 * Subjects must have lived outside of Japan no more than 10 years * Non-smoker or smokes fewer than 10 cigarettes/day Exclusion criteria: * History of asthma, anaphylaxis or anaphylactoid reactions, severe allergic responses * History of sensitivity to heparin or heparin-induced thrombocytopenia * History of alcohol/drug abuse or dependence within 12 months of the study * Positive syphilis, HIV antibody, Hepatitis B, Hepatitis C * History of cholecystectomy or biliary tract disease or history of liver disease * Participation in a clinical study within 30 days prior to first dose * Subject has been exposed to more than 4 chemical entities within 12 months * Positive urine drug and alcohol at screening * Subject has any medical history or clinically relevant abnormality that would make the subject ineligible for inclusion due to safety reasons.