In the treatment of glaucoma, trabeculectomy surgery provides a drainage system for the eye and allows for the lowering of the pressure inside the eye. The flow through the surgically created fistula determines the intraocular pressure. Titrating suture tightness is important to achieving the desired post-operative intraocular pressure. This process is not straightforward and intraocular pressures are often too high or too low post-operatively.
The use of an anterior chamber infusion system to deliver fluid into the eye during trabeculectomy surgery may be of benefit in this process and may have other benefits as well which may result in better outcomes. Thus, the hypothesis of this study is that the use of an anterior chamber infusion system improves success of trabeculectomy surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Trabeculectomy with anterior chamber infusion system
Standard trabeculectomy surgery
Hotel Dieu Hospital, Queen's University
Kingston, Ontario, Canada
Toronto Western Hospital, University of Toronto
Toronto, Ontario, Canada
surgical success: intraocular pressure lowered by 30% and functional filtering bleb
Time frame: 2 weeks, 1 month, 3 months, 6 months and 1 year post surgery
Need for laser suture lysis
Time frame: any point post operatively
complications: aqueous misdirection, suprachoroidal hemorrhage, anterior chamber shallowing
Time frame: any time post operatively
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