Hormone Dynamics and Bone Mineral Density in Anorexia Nervosa v. Hypothalamic Amenorrhea

Massachusetts General Hospital61 enrolled

Overview

The purpose of this study is to determine whether the hormone dynamics in women with anorexia nervosa and hypothalamic amenorrhea is related to bone loss in those populations.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Anorexia Nervosa Hypothalamic Amenorrhea Obesity

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Amenorrhea for at least three months (unless participating as healthy control) * Normal TSH or free thyroxine (free T4). Exclusion Criteria: * A condition known to affect bone metabolism, including Cushing's syndrome or renal failure, with the exception of bone fracture. * Any medication known to affect bone metabolism within 3 months of the study, including estrogen and progestins. Patients receiving depot medroxyprogesterone (Depo-Provera) will be excluded from participating for 6 months after their last injection. * Pregnant and/or breastfeeding. * Diabetes mellitus. * Active substance abuse, including alcohol.

Locations (1)

Massachusetts General Hospital

Boston, Massachusetts, United States

Data from ClinicalTrials.gov

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