A Study to Compare the Safety and Drug Levels in Blood When Using Various Forms of GSK189075 Given to Healthy Subjects

Inclusion Criteria: * Are a healthy, non-smoking adult, 18 to 55 years old. * Are not overly thin or overly heavy for your height. * Are a female who is unable to have children, or is willing to use birth control throughout the study. * Are willing and able to follow all study-related instructions provided by the site staff. - Are willing to provide signed consent. Exclusion Criteria: * Are a pregnant or a nursing female. * Have a past or current disease such as heart, liver, kidney, blood, brain, or other disease. * Have had certain infections within 4 weeks before the expected the first dose of study drug. * Have HIV or hepatitis, or have alcohol in your system at the screening visit. * Have a history of alcohol abuse. * Have been in another research study in the last month or have taken certain medications in the 2 weeks before study drug would be taken. * Have laboratory tests that are outside the normal range.