Evaluate Low Doses of AEGR-733 on Hepatic Fat Accumulation by MRS

Inclusion Criteria: 1. LDL-C between 100 and 190 mg/dL 2. Hepatic fat under 6.2% per MRS Exclusion Criteria: 1. Pregnant or lactating females 2. Uncontrolled hypertension \>180/95 mmHg 3. Chronic renal insufficiency - serum creatinine \>2.5 mg/dL at screen 4. Liver disease; i.e., hepatitis, cirrhosis 5. Major surgery within 3 months of screen 6. Cardiac insufficiency 7. Hx of malignancy other than basal or squamous cell within past 5 yrs 8. Participation in any investigational drug study within 6 wks of screen 9. Prior exposure to AEGR-733 in past 12 months 10. Serious or unstable medical or psychological conditions 11. More than one alcoholic drink per day 12. Regular consumption of grapefruit juice or meds known to be metabolized by CYP 3A4 13. Currently taking corticosteroids 14. Other lipid-lowering meds (washout permitted) 15. Fish oil, niacin grater than 200 mg/day and herbal weight loss products (washout permitted) 16. Acute CVD or event within previous 6 months 17. Diabetes Mellitus 18. Hepatitis B or C 19. Medicated COPD 20. Idiopathic pulmonary fibrosis 21. G.I. disorders that cause chronic diarrhea 22. Fasting triglycerides =/\> 400 mg/dL 23. Body Mass Index \> 35kg/m2