Nutritional and Metabolic Evaluation of a Tube Feeding Immune Enhancing Diet in ICU Patients

Inclusion Criteria: * 18\<age\<89, ASA score\<4 , SAPS II score\>10 * requiring the administration of an exclusive tube feeding nutrition during 7 days and beginning at the latest in the three days following the aggression * ICU patients hospitalized for: * neurologic affections * pneumopathy * major abdominal surgery or serious acute pancreatitis * written informed consent Exclusion Criteria: * pregnancy or breast feeding * immunosuppressive therapy * radiotherapy or chemotherapy in the last six month * uncontrolled septic choc * auto-immune disease * hepatic,renal or digestive insufficiency * hyperlipidemia * diabetes mellitus type 1 * digestive malabsorption * life threatening situation * treatments with growing hormone, glutamine or its metabolites or precursors such as ornithine alpha keto glutarate