Pain Processing in Anxiety and Depression

Danish Pain Research Center71 enrolled

Overview

The purpose of the study is to investigate pain, anxiety and depression in patients with panic anxiety disorders without pain or depression without pain compared with healthy volunteers

Study Type

OBSERVATIONAL

Enrollment

Conditions

Pain Anxiety Depression

Interventions

ObservationOTHER

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 75 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with panic disorder or depression Exclusion Criteria: * Treatment with antidepressants, anticonvulsants or any other pain medication except paracetamol, SSRI and benzodiazepines * Serious or unstable medical disease * Prior or present diagnosis of mania, bipolar or psychotic disorder, delirium, suicidal, drug and alcohol dependence, severe agitation * Patients who cannot cooperate and do not understand Danish

Locations (1)

Danish Pain Research Center, Aarhus University Hospital

Aarhus, Denmark

Outcomes

Primary Outcomes

Quantitative sensory testing

Time frame: 3-4 hours

Secondary Outcomes

Symptom checklist 92

Time frame: 3-4 hours

Hamilton Depression and Anxiety Rating Scale

Time frame: 3-4 hours

Major Depression Inventory

Time frame: 3-4 hours

GAD-10 Anxiety Scale

Time frame: 3-4 hours

Health Survey SF-36

Time frame: 3-4 hours

McGill Pain Questionnaire

Time frame: 3-4 hours

Sweat test

Time frame: 3-4 hours

Heart rate variability testing

Time frame: 3-4 hours

Coping Strategy Questionnaire

Time frame: 3-4 hours

Pain Catastrophizing Scale

Time frame: 3-4 hours

Pain rating (VAS)

Time frame: 3-4 hours

Interview

Time frame: 3-4 hours

Data from ClinicalTrials.gov

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