Study Of CP-751,871 In Patients With Ewing's Sarcoma Family Of Tumors

Progression-Free Survival (PFS)

PFS was the time in months from start date to date of first documentation of progression, death due to any cause or symptomatic deterioration (global deterioration of health status requiring discontinuation of treatment).

Time frame: Baseline and every cycle (4 weeks), until progression or death

Overall Survival (OS)

Time in months from enrollment to death. For participants who are alive, overall survival was censored at the last contact.

Time frame: Baseline and every 2 cycles (8 weeks), until death or up to 6 cycles after date of enrollment

Maximum Observed Plasma Concentration (Cmax)

Time frame: Cycle 1 and Cycle 5: 1 hour post-infusion on Day 1

Minimum Observed Plasma Trough Concentration (Cmin)

Cmin is the concentration at the end of treatment cycle (next cycle predose).

Time frame: Cycle 6: predose on Day 1

Plasma Concentration at End of Infusion (Cendinf)

Time frame: Cycle 1 Day 2 and Cycle 5 Day 1

Area Under the Curve From Time Zero to End of Dosing Interval (AUCtau)