Corneal Cross Linking is new treatment modality for patients with keratoconus. A keratoconus is characterized by progressive bulging and thinning of the eye's cornea. Keratoconus is a potentially severely sight impairing condition that may necessitate corneal transplantation in the progressive state. Corneal Cross Linking is designed to * increase the cornea's mechanical stability * to stop progression of bulging and thinning of the cornea * to prevent the need for corneal transplantation Corneal Cross Linking is performed by 1. Applying Riboflavin (Vitamin B2) eye drops every 2 minutes for 30 minutes to the cornea 2. Illuminating the cornea with UV-light This register of Corneal Cross Linking procedures performed in Germany serves to * gather long-term results * detect rare complications and side-effects * evaluate the efficacy in a large number of patients
Study Type
OBSERVATIONAL
Enrollment
7,500
Apply Riboflavin 0.1% in Dextran 500 20% in NaCl solution Illuminate with UV-light of 365 nm wave-length and 3.0 mW/cm² intensity at 5 cm distance
University of Saar
Homburg, Germany
Augenklinik am St. Franziskus Hospital
Münster, Germany
Keratometry
Time frame: yearly
Slit-lamp biomicroscopical findings
Time frame: yearly
Best corrected Visual Acuity
Time frame: Yearly
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