Finding out how fast azelastine nasal spray works in subjects with hay fever.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
70
One Astelin spray per nostril plus one placebo tablet. In Cross-Over-Design with other arms.
One placebo spray per nostril plus one Loratadine 10 mg tablet. In Cross-Over-Design with other arms.
One placebo spray per nostril plus one 10 mg Cetirizine tablet. In Cross-Over-Design with other arms.
Unnamed facility
Kingston, Ontario, Canada
Onset of action measured by change in total nasal symptom score Until "Onset of action" = until drug demonstrates and maintains a change greater than placebo compared to baseline
Time frame: Up to 6 hours
Change from baseline for individual symptoms of allergic seasonal rhinitis; overall assessment of efficacy
Time frame: Effect over 6 hours
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One placebo spray per nostril plus one placebo tablet. In Cross-Over-Design with other arms.