Efficacy of Pantoprazole in Patients Older Than 12 Years Who Have Symptoms of Non-Erosive Reflux Disease (NERD) or Erosive Gastroesophageal Reflux Disease (eGERD)

Nycomed1,995 enrolled

Overview

The aim of the study was to evaluate the effect of 7 days treatment with Pantoprazole 40 mg and 20 mg on symptoms in patients with NERD (non-erosive reflux disease) or eGERD (erosive gastroesophageal reflux disease) in clinical practice. During the study, the patients had to complete a short version of a patient-orientated, self-assessed reflux questionnaire (ReQuest™ in Practice).

Study Type

OBSERVATIONAL

Enrollment

1,995

Conditions

Gastroesophageal Reflux Disease

Interventions

PantoprazoleDRUG

Observational, non-interventional study (NIS). The physician decided about dosage according to individual needs (20 or 40 mg pantoprazole, once daily).

Eligibility

Sex: ALLMin age: 12 Years

Medical Language ↔ Plain English

Main inclusion criteria: * Outpatients with erosive gastro-esophageal reflux disease (eGERD according to Los Angeles classification grade A-D) or non-erosive reflux disease (NERD) Main exclusion criteria: * Criteria as defined in the Summary of Product Characteristics (Chapter 4.3)

Locations (259)

Outcomes

Primary Outcomes

Patient's Assessment of General Well-being During the Last 24 Hours (Diaries; ReQuest™ in Practice)

Assessment on a scale: Severity from 0=Excellent to 10=Extremely bad

Time frame: 7 days

Patient's Assessment of Acid Complaints During the Last 24 Hours (Diaries; ReQuest™ in Practice)