Primary objective: To compare long-term glycemic control and preservation of beta cell function when basal insulin or sulfonylurea is added on metformin in the early Type 2 Diabetes Mellitus patients Secondary objective: To assess the change of insulin resistance, microvascular complication incidence, patient satisfaction with treatment
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
75
Once daily in the morning
Once daily in the morning
At least 1000 mg/day
Sanofi-aventis
Seoul, South Korea
ß-cell Function parameter
Time frame: From the signature of the Informed Consent Form (ICF) up to the end of study
Glucose Homeostasis and glycemic control status
Time frame: From the signature of the Informed Consent Form (ICF) up to the end of study
Insulin resistance parameter, Hypoglycemic episode, symptomatic, Weight change, Lipid profile, Inflammatory markers (CRP, Adiponectin, etcs), Patient satisfaction with diabetes treatment, Urine analysis, Creatinine
Time frame: End of the study
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