Surgery Versus No Surgery for Osteoarthritis (OA) of the Knee

University of Western Ontario, Canada188 enrolled

Overview

The purpose of this study is to discover whether arthroscopic surgery is helpful in controlling the symptoms of osteoarthritis of the knee.

Although arthroscopic surgery has been widely used for osteoarthritis of the knee, scientific evidence to support its efficacy is lacking. This study will compare optimized physical and medical therapy alone with arthroscopic treatment in addition to optimized physical and medical therapy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

188

Conditions

Osteoarthritis of the Knee

Interventions

Arthroscopic surgeryPROCEDURE

Arthroscopic surgery to treat unresolved symptoms of osteoarthritis of the knee

Physical and medical therapyOTHER

Treatment with physical and medical therapy alone

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Idiopathic or secondary osteoarthritis of the knee with Grade II to IV radiographic severity as defined by the modified Kellgren and Lawrence classification Exclusion Criteria: * Patients with inflammatory or post-infectious arthritis * Those who had undergone previous arthroscopic treatment for knee osteoarthritis * Those with isolate Grade III to IV medical compartment osteoarthritis with greater than 5 degrees of varus deformity.

Locations (1)

London Health Sciences Centre - University Hospital

London, Ontario, Canada

Outcomes

Primary Outcomes

Function, pain and quality of life based on the WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) scores

Time frame: 2 years

Secondary Outcomes

Health utility using the Standard Gamble Technique

Time frame: 24 months

Data from ClinicalTrials.gov

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