A Comparative Study of the Efficacy of Transcatheter Arterial Chemoembolization (TACE) and Transcatheter Arterial Pegylated Interferon Embolization (TAIE) for Liver Cancer

Hospital Authority, Hong Kong100 enrolled

Overview

Primary: To compare the efficacy of TACE and TAIE. Secondary: To compare the side effects of TACE and TAIE. The outcome measurements include survival benefit and tumour regression induced by the two therapies.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

100

Conditions

Carcinoma, Hepatocellular

Interventions

Transcatheter Arterial Chemoembolization (TACE)PROCEDURE

Transcatheter Arterial Pegylated Interferon Embolization (TAIE)PROCEDURE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Confirmed hepatocellular carcinoma not suitable for surgery Exclusion Criteria: * Portal vein thrombosis * Severe arteriovenous shunt * Bilirubin level \> 50 umol/mL * Prothrombin time \> 5 seconds

Locations (1)

Queen Mary Hospital

Hong Kong, China

RECRUITING

Outcomes

Primary Outcomes

regression of tumour size

Time frame: assessment every 6 months

Secondary Outcomes

side effects

Time frame: every treatment given every 8 - 12 weeks

Central Contacts

Man Fung Yuen, Prof

CONTACT

(852) 2855 5311 mfyuen@hkucc.hku.hk

Data from ClinicalTrials.gov

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