Tolerability and Efficacy of Ibuprofen 800 mg in a Walking Model of Osteoarthritis Pain (0000-057)

Inclusion Criteria: * The primary source of pain is the study knee of one lower extremity * Patient is willing to limit alcohol and caffeine intake * Aside from osteoarthritis, patient is in generally good health * Patient is capable of completing protocol specified walks * Patient is able to understand and complete questionnaires in English * Patient has previously benefited from the use of either NSAIDs, COX-2 inhibitors, or acetaminophen Exclusion Criteria: * Patient has another condition which could interfere with evaluating pain in the knee being tested * Patient is not able to take a non-steroidal anti-inflammatory drug (NSAID) such as ibuprofen * Patient has a history or current evidence of stroke, transient ischemic attack, liver disease or cancer * Patient has a history or current evidence of dizziness, unsteadiness, or falling * Patient has congestive heart failure, unstable angina or uncontrolled high blood pressure * Patient has a history of stomach, digestive track, or small intestine surgery * Patient is unable to complete the study questionnaires in English