To assess the efficacy of lanreotide in controling total liver volume in patients with polycystic livers this study will be performed. A minimum of 38 patients will be recruited and randomized (1:1) to receive either verum or placebo. Lanreotide is already used in other disease states and found to be safe and non-toxic.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
38
University Hospital Gasthuisberg
Leuven, Belgium
Radboud University Medical Center
Nijmegen, Netherlands
Reduction of total liver volume as determined by CT scan
Time frame: 6 months
Reduction of liver volume and individual cyst volume on CT scan.
Time frame: 6 months
Change of kidney volume and individual cyst volume on CT scan
Time frame: 6 months
Symptom evaluation by (validated) questionnaires
Time frame: 6 months
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