CRAIL - Controlled Reperfusion of the Acutely Ischemic Limb

Inclusion Criteria: * Patients aged 18 years or older * Patients with arterial occlusion of one or both lower limbs with acute decompensated ischemia (Rutherford IIA to III) * Informed consent of the patient Exclusion Criteria: * Previous attempt of recanalisation (e.g. lysis therapy) * Known A. poplitea aneurysm of the affected extremity * Severe heart failure NYHA IV * Known atrial thrombus * Terminal renal insufficiency (creatinine \>10mg/dl or current dialysis therapy, previous transplantation of kidney) * Hypersensitivity to allopurinol * Hypersensitivity to one component part of the reperfusion solution * Participation in a clinical trial during the study or 30 days before * Pregnancy or lactation * Patient incapable of contracting or not able to understand the character, meaning and consequences of the clinical trial * Abuse to drugs or alcohol