Effect of Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist (NAVA) in Chronic Obstructive Pulmonary Disease (COPD) Patients

Policlinico Hospital15 enrolled

Overview

The investigators' aim is to study the effect of pressure support ventilation at two levels of PEEP and Pressure Support versus neurally adjusted ventilatory assist (NAVA) in COPD patients.

In this study, two levels of pressure support and PEEP during pressure support ventilation are compared with neurally adjusted ventilatory assist (NAVA) in COPD patients by measuring respiratory mechanics, intrinsic PEEP, work of breathing and patient's level of comfort.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

PSV and NAVAPROCEDURE

evaluated the effect of PSV and NAVA on breathing pattern, respiratory effort, gas exchange and level of breathing comfort in COPD patients

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Stable COPD patients during non invasive mechanical ventilation Exclusion Criteria: * Haemodynamic instability * Coma

Locations (1)

Policlinico Hospital

Milan, Italy

Outcomes

Primary Outcomes

Respiratory mechanics, gas exchange, work of breathing

Time frame: 5 minutes

Secondary Outcomes

Comfort of breathing

Time frame: 5 minutes

Data from ClinicalTrials.gov

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