Study on VCD/IE in the Patients With Ewing's Sarcoma Family of Tumors (ESFT)

Inclusion Criteria: * Age range 10-65 years old * Histological confirmed ESFT * No previous therapy * ECOG performance status less than 2 * Life expectancy of more than 12 weeks * Normal laboratory values: hemoglobin\>8.0g/dl, neutrophil\>2×109/L, platelet \> 80×109/L, Hb \> 80×1012/L, serum creatine \< 1×upper limitation of normal(ULN), serum bilirubin \< 1.5×ULN, ALT and AST \< 2.5×ULN Exclusion Criteria: * Pregnant or lactating women * Received treatment for the disease previously * Serious uncontrolled diseases and intercurrent infection * The evidence of CNS metastasis and bone marrow involvement * History of other malignancies except cured basal cell carcinoma of skin and carcinoma in-situ of uterine cervix * History of allergy to the drugs in this trial * Abnormal LVEF level