Supplementation With Vitamin D, Calcium or Both on Calcium Absorption and Bone Mineral Content in Children With JRA

University of Missouri-Columbia24 enrolled

Overview

2000 international units (IU) vitamin D, 1 gram (gm) calcium, or both given to children with Juvenile Rheumatoid Arthritis (JRA) may increase percent true calcium absorption, bone mineral turnover and/or bone mineralization.

Supplementation With 2000 IU Vitamin D, 1 gm Calcium or Both on Calcium Absorption and Bone Mineralization in Children With Juvenile Rheumatoid Arthritis may increase percent true calcium absorption, bone mineral turnover and/or bone mineralization.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Juvenile Rheumatoid Arthritis

Interventions

CholecalciferolDIETARY_SUPPLEMENT

2000IU Cholecalciferol P.O. Q.D.

CalciumDIETARY_SUPPLEMENT

1 gm calcium as calcium carbonate

Calcium and cholecalciferolDIETARY_SUPPLEMENT

2000IU cholecalciferol and 1 gm calcium P.O. Q.D. for 6 months

Eligibility

Sex: ALLMin age: 3 YearsMax age: 15 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Juvenile Rheumatoid arthritis Exclusion Criteria: * Steroid use

Locations (1)

University of Missouri Hospitals and clinics

Columbia, Missouri, United States

Outcomes

Primary Outcomes

Percent true calcium absorption

Time frame: After 6 months of treatment

Secondary Outcomes

Bone Mineralization by Dual Energy x-ray absorption

Time frame: After 6 months treatment plus 3 month washout

Data from ClinicalTrials.gov

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