A Randomised Study Comparing Tissue Conservation in Conventional Versus Mohs' Surgery of Basal Cell Carcinoma

NHS Tayside30 enrolled

Overview

We have compared to types of surgery to assess which one leaves the smaller surgical defect.

Patients with a clinical diagnosis of a nodular basal cell carcinoma of less than 1 centimetre and 1 centimetre away from eyes, nose and ears were either randomized to undergo Mohs Micrographic Surgery or standard surgical excision. After the tumour had been removed the defect was measured.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Carcinoma, Basal Cell

Interventions

standard surgeryPROCEDURE

excision with 4 mm margins

Mohs micrographic surgeryPROCEDURE

excision of basal cell carcinoma with 2 mm margins and immediate examination of margins for residual tumour. residual tumour was excised until complete tumour removal was achieved.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Subjects with a clinical diagnosis of a nodular basal cell carcinoma of less than 1 cm, 1 cm away from eye, nose or ears Exclusion Criteria: * Subjects of less than 18 years of age * Subjects unable to comply with instructions, * Immunosuppressed subjects

Locations (1)

Ninewells Hospital and Medical School

Dundee, United Kingdom

Outcomes

Primary Outcomes

defect size after surgery

Time frame: immediately after surgery

Data from ClinicalTrials.gov

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